PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G40140.1
Common NameATSZF2, CZF1, SZF2, T07M07.3, T7M7.3, ZFAR1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C3H
Protein Properties Length: 597aa    MW: 66153.4 Da    PI: 7.0574
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G40140.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH24.74e-08259279526
                  --SGGGGTS--TTTTT-SS-SS CS
      zf-CCCH   5 lCrffartGtCkyGdrCkFaHg 26 
                  +C+ f++ G C+ Gd+C +aHg
  AT2G40140.1 259 PCPEFRK-GSCPKGDSCEYAHG 279
                  8******.*************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.25.40.203.4E-1526174IPR020683Ankyrin repeat-containing domain
SuperFamilySSF484034.82E-1427157IPR020683Ankyrin repeat-containing domain
CDDcd002045.98E-1231174No hitNo description
SMARTSM002488.3E-476106IPR002110Ankyrin repeat
PROSITE profilePS5029713.68176157IPR020683Ankyrin repeat-containing domain
PfamPF136377.7E-977129No hitNo description
SMARTSM002484111143IPR002110Ankyrin repeat
PROSITE profilePS5010313.976254281IPR000571Zinc finger, CCCH-type
SMARTSM003566.3E-5254280IPR000571Zinc finger, CCCH-type
PfamPF006421.7E-5259279IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.101.0E-5259280IPR000571Zinc finger, CCCH-type
PROSITE profilePS501036.465289313IPR000571Zinc finger, CCCH-type
SMARTSM0035637289312IPR000571Zinc finger, CCCH-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009409Biological Processresponse to cold
GO:0010200Biological Processresponse to chitin
GO:0050832Biological Processdefense response to fungus
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 597 aa     Download sequence    Send to blast
MCGAKSNLCS SKTLTEVEFM RQKSEDGASA TCLLEFAACD DLSSFKREIE ENPSVEIDES  60
GFWYCRRVGS KKMGFEERTP LMVAAMYGSM EVLNYIIATG RSDVNRVCSD EKVTALHCAV  120
SGCSVSIVEI IKILLDASAS PNCVDANGNK PVDLLAKDSR FVPNQSRKAV EVLLTGIHGS  180
VMEEEEEELK SVVTKYPADA SLPDINEGVY GTDDFRMFSF KVKPCSRAYS HDWTECPFVH  240
PGENARRRDP RKYPYTCVPC PEFRKGSCPK GDSCEYAHGV FESWLHPAQY RTRLCKDETG  300
CARRVCFFAH RRDELRPVNA STGSAMVSPR SSNQSPEMSV MSPLTLGSSP MNSPMANGVP  360
LSPRNGGLWQ NRVNSLTPPP LQLNGSRLKS TLSARDMDME MELRFRGLDN RRLGDLKPSN  420
LEETFGSYDS ASVMQLQSPS RHSQMNHYPS SPVRQPPPHG FESSAAMAAA VMNARSSAFA  480
KRSLSFKPAP VASNVSDWGS PNGKLEWGMQ RDELNKLRRS ASFGIHGNNN NSVSRPARDY  540
SDEPDVSWVN SLVKENAPER VNERVGNTVN GAASRDKFKL PSWAEQMYID HEQQIVA
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.276630.0leaf| root| seed| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453608240.0
Genevisible263379_at0.0
Expression AtlasAT2G40140-
AtGenExpressAT2G40140-
ATTED-IIAT2G40140-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots and anthers. {ECO:0000269|PubMed:17609218}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in salt stress response. May positively modulate plant tolerance to salt stress. {ECO:0000269|PubMed:17609218}.
Function -- GeneRIF ? help Back to Top
  1. AtSZF1 and AtSZF2 negatively regulate the expression of salt-responsive genes and play important roles in modulating the tolerance of Arabidopsis plants to salt stress.
    [PMID: 17609218]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G40140.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salt stress. {ECO:0000269|PubMed:17609218}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G40140
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF0852790.0AF085279.1 Arabidopsis thaliana ABA-regulated gene cluster, complete sequence.
GenBankAY0930160.0AY093016.1 Arabidopsis thaliana putative CCCH-type zinc finger protein (At2g40140) mRNA, complete cds.
GenBankAY1289370.0AY128937.1 Arabidopsis thaliana putative CCCH-type zinc finger protein (At2g40140) mRNA, complete cds.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001031517.10.0zinc finger CCCH domain-containing protein 29
RefseqNP_181543.10.0zinc finger CCCH domain-containing protein 29
SwissprotQ9XEE60.0C3H29_ARATH; Zinc finger CCCH domain-containing protein 29
TrEMBLR0HRW60.0R0HRW6_9BRAS; Uncharacterized protein
STRINGAT2G40140.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM87726107
Representative plantOGRP7091569
Publications ? help Back to Top
  1. Wang ML, et al.
    A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07.
    Genome Res., 1999. 9(4): p. 325-33
    [PMID:10207155]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Gutierrez RA,Ewing RM,Cherry JM,Green PJ
    Identification of unstable transcripts in Arabidopsis by cDNA microarray analysis: rapid decay is associated with a group of touch- and specific clock-controlled genes.
    Proc. Natl. Acad. Sci. U.S.A., 2002. 99(17): p. 11513-8
    [PMID:12167669]
  4. Whitham SA, et al.
    Diverse RNA viruses elicit the expression of common sets of genes in susceptible Arabidopsis thaliana plants.
    Plant J., 2003. 33(2): p. 271-83
    [PMID:12535341]
  5. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  6. Goda H, et al.
    Comprehensive comparison of auxin-regulated and brassinosteroid-regulated genes in Arabidopsis.
    Plant Physiol., 2004. 134(4): p. 1555-73
    [PMID:15047898]
  7. Ko JH,Han KH,Park S,Yang J
    Plant body weight-induced secondary growth in Arabidopsis and its transcription phenotype revealed by whole-transcriptome profiling.
    Plant Physiol., 2004. 135(2): p. 1069-83
    [PMID:15194820]
  8. Hampton CR, et al.
    Cesium toxicity in Arabidopsis.
    Plant Physiol., 2004. 136(3): p. 3824-37
    [PMID:15489280]
  9. Vogel JT,Zarka DG,Van Buskirk HA,Fowler SG,Thomashow MF
    Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis.
    Plant J., 2005. 41(2): p. 195-211
    [PMID:15634197]
  10. Stanley Kim H, et al.
    Transcriptional divergence of the duplicated oxidative stress-responsive genes in the Arabidopsis genome.
    Plant J., 2005. 41(2): p. 212-20
    [PMID:15634198]
  11. Davletova S,Schlauch K,Coutu J,Mittler R
    The zinc-finger protein Zat12 plays a central role in reactive oxygen and abiotic stress signaling in Arabidopsis.
    Plant Physiol., 2005. 139(2): p. 847-56
    [PMID:16183833]
  12. Vergnolle C, et al.
    The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions.
    Plant Physiol., 2005. 139(3): p. 1217-33
    [PMID:16258011]
  13. Delaney KJ, et al.
    Calmodulin interacts with and regulates the RNA-binding activity of an Arabidopsis polyadenylation factor subunit.
    Plant Physiol., 2006. 140(4): p. 1507-21
    [PMID:16500995]
  14. Truman W,de Zabala MT,Grant M
    Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance.
    Plant J., 2006. 46(1): p. 14-33
    [PMID:16553893]
  15. Hoen DR, et al.
    Transposon-mediated expansion and diversification of a family of ULP-like genes.
    Mol. Biol. Evol., 2006. 23(6): p. 1254-68
    [PMID:16581939]
  16. AbuQamar S, et al.
    Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection.
    Plant J., 2006. 48(1): p. 28-44
    [PMID:16925600]
  17. Kaplan B, et al.
    Rapid transcriptome changes induced by cytosolic Ca2+ transients reveal ABRE-related sequences as Ca2+-responsive cis elements in Arabidopsis.
    Plant Cell, 2006. 18(10): p. 2733-48
    [PMID:16980540]
  18. Sato M, et al.
    A high-performance, small-scale microarray for expression profiling of many samples in Arabidopsis-pathogen studies.
    Plant J., 2007. 49(3): p. 565-77
    [PMID:17181774]
  19. Willems G, et al.
    The genetic basis of zinc tolerance in the metallophyte Arabidopsis halleri ssp. halleri (Brassicaceae): an analysis of quantitative trait loci.
    Genetics, 2007. 176(1): p. 659-74
    [PMID:17409091]
  20. Sun J, et al.
    The CCCH-type zinc finger proteins AtSZF1 and AtSZF2 regulate salt stress responses in Arabidopsis.
    Plant Cell Physiol., 2007. 48(8): p. 1148-58
    [PMID:17609218]
  21. Libault M,Wan J,Czechowski T,Udvardi M,Stacey G
    Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.
    Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11
    [PMID:17722694]
  22. Wang D, et al.
    Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.
    BMC Genomics, 2008. 9: p. 44
    [PMID:18221561]
  23. Kim DH, et al.
    SOMNUS, a CCCH-type zinc finger protein in Arabidopsis, negatively regulates light-dependent seed germination downstream of PIL5.
    Plant Cell, 2008. 20(5): p. 1260-77
    [PMID:18487351]
  24. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  25. Khandelwal A,Elvitigala T,Ghosh B,Quatrano RS
    Arabidopsis transcriptome reveals control circuits regulating redox homeostasis and the role of an AP2 transcription factor.
    Plant Physiol., 2008. 148(4): p. 2050-8
    [PMID:18829981]
  26. Kanchiswamy CN, et al.
    Regulation of Arabidopsis defense responses against Spodoptera littoralis by CPK-mediated calcium signaling.
    BMC Plant Biol., 2010. 10: p. 97
    [PMID:20504319]
  27. Klopffleisch K, et al.
    Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis.
    Mol. Syst. Biol., 2011. 7: p. 532
    [PMID:21952135]
  28. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]